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CBI Program
Department of Chemistry
138 Remsen Hall
3400 N. Charles Street
Baltimore, MD 21218

410-516-7427 phone
410-516-8420 fax

Thesis Research

As a CBI student you will begin your thesis research after selecting an advisor in May of your first year at Johns Hopkins. Beginning in the Fall semester of your second year at Johns Hopkins you will meet annually with your Research Committee to discuss your Ph.D. thesis research.

Although CBI faculty members come from many departments, you will be a member of the Chemistry-Biology Interface program, and will receive the Ph.D. degree in Chemical Biology, regardless of the department in which your thesis advisor holds her/his primary appointment.

Research Committee
Once you have selected your thesis lab and have started your dissertation research you will assemble a committee of 3 CBI preceptors (including your advisor) to act as your Research Committee. You will meet with your thesis commit once each year to discuss the progress that you have made and the goals of your Ph.D. dissertation research. When you are nearing the completion of your degree you will meet with your Research Committee no less than 6 months before defending your thesis.

CBI Research Topics
Research done in CBI labs spans a wide range of topics at the Chemistry-Biology Interface.  Topics include:

• Enzyme mechanisms, inhibitors, and metabolic pahtways
• DNA replication, damage, and repair
• Using small molecules to probe signal transduction, gene regulation, angiogenesis, and other biological processes
• Synthetic methods and medicinal chemistry
• Synthetic modeling of metalloenzymes
• Macromolecular structure determination by NMR and X-ray crystallography
• Development of spectroscopic and instrumental methods for structure determination and studies on molecular dynamics
• RNA and protein folding
• Chemical tools for biotechnology

For a complete list of our faculty and their individual research interests please click here: CBI Faculty

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